Method[ edit ] Positive reaction means: A 10mm or more induration after 48hrs B 5mm or above nodule after 21 days. The lump indicates that the antigen has been injected at the correct depth. The injection site is labeled and examined at 48hours and 21 days later to see if there is a reaction. People with dermatitis or other skin irritations should have the test performed on an unaffected part of the body. The more familiar the child is with what will happen and why, the less anxiety he or she will feel. There may also be mild itching at the site of injection afterwards.
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The lepromin skin test is used to determine what type of leprosy a person has. Alternative Names Leprosy skin test; Hansen disease - skin test How the Test is Performed A sample of inactivated unable to cause infection leprosy-causing bacteria is injected just under the skin, often on the forearm, so that a small lump pushes the skin up. The lump indicates that the antigen has been injected at the correct depth.
The injection site is labeled and examined 3 days, and again 28 days later to see if there is a reaction. How to Prepare for the Test People with dermatitis or other skin irritations should have the test performed on an unaffected part of the body.
If your child is to have this test performed, it may be helpful to explain how the test will feel, and even demonstrate on a doll. Explain the reason for the test. Knowing the "how and why" may reduce the anxiety your child feels. How the Test will Feel When the antigen is injected, there may be a slight stinging or burning. There may also be mild itching at the site of injection afterward. Why the Test is Performed Leprosy chronic and potentially disfiguring infection if left untreated.
It is caused by Mycobacterium leprae bacteria. This test is a research tool that helps classify the different types of leprosy. It is not recommended as the main method to diagnose leprosy. People with a particular type of leprosy, called lepromatous leprosy, will also have no skin reaction to the antigen.
What Abnormal Results Mean A positive skin reaction may be seen in people with specific forms of leprosy, such as tuberculoid and borderline tuberculoid leprosy. People with lepromatous leprosy will not have a positive skin reaction. Risks There is a very small risk for an allergic reaction, which may include itching and rarely, hives.
References Dupnik K. Leprosy Mycobacterium leprae. Philadelphia, PA: Elsevier; chap Hansen disease. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Any duplication or distribution of the information contained herein is strictly prohibited. Information developed by A.
Please discuss with your doctor any questions or concerns you may have. Coronavirus update As coronavirus spreads, UCSF experts explain when to call the doctor, how testing works and how to protect your family.
Lepromin Skin Test (Leprosy Skin Test)
How is the test performed? A lepromin skin test is performed by injecting a small sample of inactivated M. The bacterium is usually injected into the forearm. A small lump will form at the injection site, indicating that the correct amount of bacterium has been injected at the correct depth in the skin for the test to be effective.
Negative Lepromin Skin Test: The lepromin skin test is not used to diagnose leprosy but to determine what type of leprosy a person has. Lepromin skin test is similar to tuberculin test. An extract of M. Lepromin test is employed mostly for the following two purposes. To classify the lesions of leprosy patients. To assess the prognosis and response to treatment.