ANTIBACTERIAL ACTIVITY OF ADHATODA VASICA PDF

International Journal of Cancer. The compound showed prominent cytotoxic activity in vitro against A lung adenocarcinoma cancer cell axhatoda. Glossary of Indian Medicinal Plants. Shade dried and coarsely powdered leaves of A. The plant contains alkaloids such as Vasicine, vasicinone, deoxyvasicine, vasicol, adhatodinine, and vasicinol [ 12 ]. Antimicrobial Activity Antibacterial and antifungal activities were carried out using disc diffusion method [ 16 ].

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International Journal of Cancer. The compound showed prominent cytotoxic activity in vitro against A lung adenocarcinoma cancer cell axhatoda. Glossary of Indian Medicinal Plants. Shade dried and coarsely powdered leaves of A. The plant contains alkaloids such as Vasicine, vasicinone, deoxyvasicine, vasicol, adhatodinine, and vasicinol [ 12 ]. Antimicrobial Activity Antibacterial and antifungal activities were carried out using disc diffusion method [ 16 ].

The free radical scavenging activity was calculated as follows:. BoxRiyadhSaudi Arabia. The present studies cover antibacterial activity of the crude methanolic extracts of 11 medicinal plants viz. Antibacterial and antifungal activities were carried out using disc diffusion method actifity 16 ]. The combined chloroform extract was washed with water, dipped, and dried over anhydrous sodium sulphate.

Cytotoxic A and antibacterila effects of Methylobacterium sp. Further elution of the column with chloroform: Vasicine hydrochloride, a new drug for interruption of pregnancy. The solutions were filtered through a membrane filter pore size 0. Antimicrobial and antimycobacterial activities of methyl caffeate isolated from Solanum torvum Swartz. Streptomycin was used as positive control for bacteria and Ketoconazole as positive control for fungi. Kulkarni [ 24 ] reported that A.

Greater antibacterial activity against Pseudomonas aeruginosa was only exhibited by Phyllanthus emblica, Pinus roxburghii, Debregeasia salicifolia and Lantana camara. International Journal antibacterlal Green Pharmacy. Vasicine showed antimicrobial activity against S. Vasicine acetate showed moderate antibacterial activity compared to Vasicine. The free radical scavenging activity was calculated as follows: The cytotoxicity was determined according to the method of Balachandran et al.

Nees Acanthaceaeknown commonly as Malabar nut tree, is a shrub growing throughout the Indian peninsula. Journal of Natural Product and Plant Resources. Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper.

Indian Journal of Medical Research. Microbial Organisms The following Gram negative, Gram positive bacteria, clinical isolates, and fungi were used for the experiment: Ignacimuthu C.

Ignacimuthu and Shanmugam [ 15 ] have reported the antitubercular activity of Vasicine acetate isolated from A. Materials and Methods 2. Antimycobacterial activity of two natural alkaloids, vasicine acetate and 2-acetyl benzylamine, isolated from Indian shrub Adhatoda vasica Ness. Potent uterine activity of alkaloid vasicine. Escherichia coli was highly resistant to all the plant extracts at all concentrations. Structure of the compounds: Journal of Obstetrics and Gynaecology of India.

In vitro antibacterial activity of selected medicinal plants from lower Himalayas. Results and Discussion The ethanol extract of A. The mobile phase was filtered through a 0.

Effect of Adhatoda vasica massage in pyorrhoea. Every year, at leastpeople die worldwide from cancer related to their workplace [ 3 ]. The crude extract of A. Published online Jan Table 4 Cytotoxic effect of Vasicine acetate against A lung adenocarcinoma cancer cell line.

Minimum Inhibitory Concentration MIC Minimum inhibitory concentration studies of the compounds were performed according to the standard reference methods for bacteria [ 17 ] and filamentous fungi [ 18 ]. TOP Related Posts.

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ANTIMICROBIAL ACTIVITY OF ADHATODA VASICA PDF

The agar well diffusion method was adopted to determine antibacterial activity against all the tested microorganisms. The selection of extracts was based on a phytochemical screening for the presence of secondary metabolites. The methanolic extract of A. The methanolic extract of the leaves was stronger than extracts based on other solvents such as chloroform and hexane, which showed moderate to weak activity, respectively.

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To use in bioprocess the silver nanoparticles should be biocompatible and free from toxic chemicals. In the present study we report a cost effective and environment friendly route for green synthesis of silver nanoparticles using Vasaka Justicia adhatoda L. This plant has been opted for the present study for its known medicinal properties and it is easily available. The antibacterial activity of these nanoparticles against Pseudomonas aeruginosa MTCC has been measured by disc diffusion method, agar cup assay and serial dilution turbidity measurement assay. The results show green synthesized silver nanoparticles, using Vasaka leaf extract, have a potential to inhibit the growth of bacteria. Electronic supplementary material The online version of this article doi

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